Peak fertility is found to be the 2-3 days prior to ovulation³, per the American Society for Reproductive Medicine. The Ayola System is designed to capture this window of fertility to maximize the chances of conception.

³ https://www.fertstert.org/article/S0015-0282(16)62849-2/fulltext

The Ayola Ring continuously measures your core body temperature and sends your temperature information to the Ayola App. The Ayola App stores and analyzes your temperature measurements to detect your fertile window. The Ayola App will notify you when it has predicted your fertile window.

Peak fertility is found to be the 2-3 days prior to ovulation⁴, per the American Society for Reproductive Medicine. The Ayola System is designed to capture this window of fertility to maximize the chances of conception.

⁴ https://www.fertstert.org/article/S0015-0282(16)62849-2/fulltext

Surprisingly, having sex outside of the fertile window improves your chances at conception as well! Sexually active women see maximal cycle-related shift in humoral immunity, which is the aspect of the immune system that involves molecules found in bodily fluids. These shifts are associated with changes in the body that help prepare it for pregnancy⁵ . In additional to immune benefits, sex outside of the fertile window provides a chance to enjoy intimacy without the added stress of trying to get pregnant. Trying to conceive may become all-consuming, but enjoying sex may make the journey even more positive.

⁵ Lorenz, T. K., Demas, G. E., & Heiman, J. R. (2015). Interaction of menstrual cycle phase and sexual activity predicts mucosal and systemic humoral immunity in healthy women. Physiology & behavior, 152, 92-98.; https://www.sciencedirect.com/science/article/pii/S0031938415301153

• Track your cervical mucus cycle: cervical secretions; changes in cervical secretions are suggestive of a preovulatory estrogen effect. If you notice when your cervical mucus becomes increasingly more slippery, clear and stretchy, your body is getting ready for ovulation.
• Track Luteinizing Hormone (LH): LH is a hormone produced by your pituitary gland. Your body always makes a small amount of LH, but just before you ovulate, you have an LH surge. Products that test for this LH surge, which usually happens 1 – 1½ days before you ovulate, must be carefully used for accuracy. To track LH, you will need to purchase LH sticks that detect your levels via urine. Typically you will urinate on the sticks soon after your cycle ends every morning until you ovulate.
• Track your temperature: basal body temperature rises shortly after ovulation, approximately 0.275 5°C, as a result of progesterone release from the corpus luteum. This method requires dedication to waking up the same time every morning and charting the results. The temperature rise can be unreliable and is usually identified retrospectively.
• Calendar Method: if you have a regular cycle that does not vary more than two days each month, you may be able to predict ovulation using the calendar calculation. Ovulation occurs approximately 14 days before the onset of menstruation. However, many women do not have such regular cycles and therefore their luteal phase may vary individually from 10 to 16 days, making it harder to predict ovulation by calendar calculations alone. Using a cycle tracking app is a great way to help keep charting of these biomarker parameters more simple. You can also use the data to show your doctor if necessary.

⁶ https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btm2.10058

The lifespan of sperm inside a woman’s body is under debate, but experts agree that it depends on cervical mucus, which provides the sperm with the nutrients and the medium they need to survive during their journey to the ovum⁷. Sperm can be damaged by the vagina’s natural acidity which protects against foreign bacteria⁸, but in the right conditions, sperm can even live up to 5⁹ or 6 days in your body after intercourse^{10; 11}. This is an incredible feat compared to the brief lifespan of a mere few hours when no cervical mucus is present¹².

⁷ Fordney-Settlage, D. (1981). A review of cervical mucus and sperm interactions in humans. International journal of fertility, 26(3), 161-169.
⁸ Suarez, S. S., & Pacey, A. A. (2006). Sperm transport in the female reproductive tract. Human reproduction update, 12(1), 23-37
⁹ UCSF Health. (2020, August 19). Conception: How It Works. Ucsfhealth.Org. https://www.ucsfhealth.org/education/conception-how-it-work
¹⁰ Fertility Awareness Methods | Natural Birth Control. (2020). Planned Parenthood. https://www.plannedparenthood.org/learn/birth-control/fertility-awareness
¹¹ What Are Some Tips & Ways to Help Get Pregnant? (2020). Planned Parenthood. https://www.plannedparenthood.org/learn/pregnancy/how-pregnancy-happens/what-are-some-tips-getting-pregnant
¹² Grünebaum, A. G. (2020, November). How Long Does Sperm Survive? Babymed. https://www.babymed.com/how-long-do-sperm-survive#:~:text=Sperm%20can%20survive%20in%20the,survive%20for%204%2D5%20days

• Body-weight: If overweight, lose weight
• Exercise: Exercise regularly
• Diet: Maintain a healthy diet with foods rich in antioxidants and take a daily multivitamin
• Habits: Don’t smoke or use recreational drugs and reduce your intake of alcohol to fewer than 5 drinks per week
• Heat: Don’t overheat you

¹³ Lifestyle and fertility: the influence of stress and quality of life on male fertility. (2020, August 25). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260894/

The Ayola Ring Ayola Ring does not need to be removed to have sexual intercourse. However, if there is any discomfort experienced by you or your partner, the ring may be removed. To enable the most accurate fertile window predictions, the sensor should be cleaned and re-inserted as soon as possible afterwards.

You may have heard that contractions from an orgasm can help sperm successfully travel to the egg. The one paper that explored this notion concluded that it’s “unlikely”¹⁴. So no need to stress if you orgasm before or after your partner does or if reaching an orgasm during intercourse is difficult for you to do.
However, we’d be remiss if we didn’t mention there’s a scientific basis to this notion. Uterine contractions do help propel sperm, but the contractions aren’t from your orgasm or even under your direct control¹⁵. Instead, these uterine contractions — which are believed to be regulated by your hormones — happen continually throughout the follicular phase of your menstrual cycle… The contractions even increase right before ovulation to give sperm an extra push in the right direction

¹⁴ No direct relationship between human female orgasm rate and number of offspring. (2013, August 1). ScienceDirect. https://www.sciencedirect.com/science/article/abs/pii/S0003347213002121
¹⁵ https://academic.oup.com/humrep/article/11/3/627/582632

While this notion is related to the idea of lying in bed after sex, we don’t have any data on whether hoisting your legs in the air after sex increases your chances of conception.
Still, this myth is a popular one in the „Trying to Conceive” community. Searching for its origin led to a research rabbit hole. One possible explanation for why the legs-up idea has gained traction is the position kind of mirrors the Trendelenburg position, which is common in medicine. In the Trendelenburg position, you lie on your back with your feet elevated. If you’ve ever been on bed rest, you may have been instructed to lie in this position. It is sometimes used to prevent preterm birth with a weakened cervix¹⁶. But again, science doesn’t show that this position conveys any conception benefits following sex.

¹⁶ Cervical incompetence prevention randomized cerclage trial: Emergency cerclage with bed rest versus bed rest alone. (2003, October 1). ScienceDirect. https://www.sciencedirect.com/science/article/abs/pii/S000293780300718X

It might seem like common sense that certain sex positions, like missionary style, would boost your chances of pregnancy. After all, penetration is deeper in the missionary position (and doggy style) than others. In reality, we don’t know if there’s an ideal position to have sex to get pregnant since scientists haven’t weighed in on this precise question.
That said, we do know that sperm are naturally programmed to swim to the egg17, no matter the position. The best answer right now is to choose sexy-time positions that feel great for you and your partner.

¹⁷Fertilization: a sperm’s journey to and interaction with the oocyte. (2010, April 1). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846064/

Ring measures temperatuire data every 6 minutes and send these data to Ayola App once every hour. Every two hours all data is trensferred to a cloud where algorithm analyse and send back sign about the fertility window infomration.

The Ayola Ring will store your temperatures for approximately 30 days and deliver them according to the syncing schedule once the app is reopened.

The Ayola App will store your temperatures for all of your cycles during the time it is paired with the Ayola Ring. Temperature graphs and cycle notes for all cycles will always be viewable on your Ayola App. The Ayola Ring can be used for up to 180 days.

Each Ayola Ring is supplied with a Bluetooth Pairing Code. The Ayola Ring will only communicate with the Ayola App if the Bluetooth Pairing Code has been entered. Being around another active Ayola Ring will not affect your results.

No. The Sensor can store up to 30 days of un-synced temperatures.

It’s important to keep your mobile device as close to your body as possible during syncing, for about one minute or until a syncing occurs. Every woman’s body is different! Depending on your anatomy, you may find placing your phone in front of you works well. Or, you may find that having it in a back pocket works best. Some women may find placing the mobile device in front of them works well, while others may need to place it closer to their side or back pocket. If syncing doesn’t work on the first try, don’t panic. Your temperature data is stored in the Sensor and will not be lost. Simply try a different position for your mobile device for the next scheduled sync.

The Ayola Ring continuously measures your core body temperature and sends your temperature information to the AYOLA App. The AYOLA App stores and analyzes your temperature measurements to detect your fertile window. The AYOLA App will notify you when it has predicted your fertile window.

Ayola is effortless and precise. You can insert Ayola in the comfort of your home to effortlessly pinpoint your fertile window and predict ovulation. Continuous core body temperature is a highly reliable way to track temperature patters to predict the fertile window (cite Coyne¹⁸). The chance for user error, as compared to other methods, is significantly reduced by Ayola’s automated data collection. It’s a wealth of information about a person’s changing fertility.

¹⁸ https://journals.physiology.org/doi/full/10.1152/ajpregu.2000.279.4.R1316

Temperature patterns, through continuous monitoring, have been established as a highly reliable marker for circadian rhythm¹⁹. By continuously monitoring a woman’s core body temperature, a subtle temperature shift associated with ovulation can be detected and the fertile window identified.

¹⁹ Brown, E. N., Choe, Y., Luithardt, H., & Czeisler, C. A. (2000). A statistical model of the human core-temperature circadian rhythm. American Journal of Physiology-Endocrinology and Metabolism, 279(3), E669-E683.

The Ayola App may generate the following notifications during your active cycle.
Fertile window – When the Ayola App detects temperature variations that indicate imminent ovulation, you will receive a notification, and your fertile window will be highlighted on the temperature graph on the “Home” screen.”

Ayola is intended for continuously measuring and recording core body temperature as an aid in ovulation prediction to aid in conception. Unlike other ovulation prediction aids that is only worn at night, Ayola is designed to be worn 24 hours per day for up to 29 days per cycle to continuously track core body temperatures.

Core body temperature should be measured continuously to see the patterns in temperature data that illustrate dynamic changes correlated to circadian rhythms which have been shown to accurately pinpoint a woman’s fertile window.

Compared to basal body temperature and other ovulation prediction methods, Continuous Core Body Temperatures (CCBT) does not require following certain rules and provides an accurate and precise prediction of ovulation. By using Ayola certain CCBT is collected night and day to catch important changes in temperature patterns that could occur at any time.”

Basal body temperature (BBT)

BBT, or your temperature at rest, is generally not sensitive enough to capture the subtle changes that occur prior to ovulation and is also affected by environmental factors such as medication, lack of sleep, and alcohol. Since BBT detects the rise in temperature after ovulation has occurred, the fertile window has ended. BBT also requires taking daily temperature at the same time every morning²⁰.

Since continuous core body temperature is collected night and day from inside the body, it is not impacted by the factors mentioned above and is able to detect temperature patterns that predict the fertile window BEFORE ovulation occurs.

Luteinizing Hormone (LH)

Ovulation predictor kits (OPK) that measure a surge in the production of LH in urine are widely used, but the days with the highest probability of getting pregnant often occur before a detectable LH surge. The surge occurs roughly 24 hours before ovulation, which may be too late for conception²¹. Also, since individual LH surges are extremely variable²², the LH surge can be missed, even by those who test daily.

CCBT measurements give women more time to have intercourse during peak fertility, maximizing the chance of conception. CCBT also avoids the limitations of LH testing with variability in the surges and duration prior to ovulation.

Sensors

Peripheral sensors (those worn on the wrist, for example) may make collecting temperature easier, however, research shows that skin temperature may not be an accurate predictor of ovulation²³. For example, temperatures taken with a wrist temperature sensor indicated sustained 3-day temperature shift in only 82% of cycles and the lowest temperature in the cycle occurred in the fertile window 41% of the time. In addition, most temporal shifts (86%) occurred on ovulation day or later²⁴.

CCBT can provide accurate and precise prediction of ovulation²⁵, and true CCBT is collected at night and day to catch changes that may occur at any time in a 24-hour period²⁶.

²⁰ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265623/
²¹ http://npr.pl/badania/timing_intercourse.pdf
²² https://www.fertstert.org/article/S0015-0282(12)02135-8/fulltext
²³ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081768/
²⁴ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265623/
²⁵ https://journals.lww.com/greenjournal/Abstract/2016/05001/Continuous,_Passive_Personal_Wearable_Sensor_to.219.aspx
²⁶ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864880/

The Ayola Ring Ayola Ring has a temperature measurement accuracy of +/- 0.1°C.

The Ayola App will store your temperatures for all of your cycles during the time it is paired with the Ayola Sensor. Temperature graphs and cycle notes for all cycles will always be viewable on your Ayola App.

The Ayola Ring is a flexible vaginal ring that is self-inserted at home. It is for vaginal use only. The Ayola Ring does not need to be inserted by a Doctor.

To ensure an accurate fertile window prediction, insert the Ayola Ring on the day your period ends (or within 24 hours). You must clean and disinfect the Ayola Ring before each use with the following instructions.
he Ayola Ring should be cleaned with a product such as DISPATCH Hospital Cleaner Disinfectant Towels™ or Oxivir Tb Wipes™ which have been tested and shown to be safe and effective. Refer to full cleaning instructions in the Instructions for Use. Never expose or submerge the sensor in boiling water; doing so will void your warranty.

• STEP 1: Disinfect Ayola Ring for first use
  Wash your hands.
  Dispense the disinfectant towel from its package or container.
  Clean the outside of the Ayola Ring with one disinfectant towel according to the instructions provided with the disinfectant towel.
  Discard used towel according to the instructions provided with the disinfectant towel.
  Dispense a second towel from its package or container.
  Disinfect the Ayola Ring by wiping all outside surfaces thoroughly according to the instructions provided with the disinfectant towel.
  Wait at least 1 minute and make sure the Ayola Ring is completely air-dried before inserting. Make sure there are no bubbles from the cleaning agent that remain.
  After 1 minute, you can rinse the sensor under running water to remove any residual cleaning agent.
• STEP 2: Prepare Ayola Ring for insertion.
  Place your thumb next to the LED window and index finger across to compress the sensor.
  Prepare the Ayola Ring by gently pressing on it to fold it into an oval shape.
  *Do not twist the Ayola Ring to insert the device, as this could damage the interior components
• STEP 3: Choose a position for inserting Ayola Sensor:
  Choose a position for inserting the Ayola Ring that is most comfortable for you.
  For example, you may lie down. You may also try squatting or standing with one leg up on a chair.
• STEP 4: Inserting Ayola Ring into your Vagina.
  Insert the compressed Ayola Ring into your vagina. Gently push it further up into your vagina using your index or middle finger. The Ayola Ring may move around slightly in your vagina. This is normal.

If you feel discomfort, the Ayola Ring may not be fully inserted. Use your clean finger to push the Ayola Ring further into your vagina. Any initial discomfort should resolve quickly. If you find that the Ayola Ring is “”dry”” to insert, apply a very small amount of standard water-based lubricant for vaginal use or a fertility-friendly lubricant such as Pre-seed®. DO NOT use gels with warming or cooling additives; the lubricant should not contain a spermicide. After insertion, wash your hands.

To ensure an accurate fertile window prediction, the Ayola Ring should be inserted on the day your period ends (or within 24 hours after your period ends)(see Section 5.5 of the IFU). Do not pair your Ayola Ring until you are ready to insert it. The Ayola Ring should not be worn during your menstrual period.
The Ayola System is not effective if you start using the Ayola Ring more than two days after the end of your period and will not allow you to pair the Ayola Ring and Ayola App.

To enable the most accurate fertile window predictions, you should start using your Ayola Ring on the last day of your period. However, you can start using your Ayola Ring up to two days after the end of your menstrual period. The Ayola Ring is not effective if you start using the Ayola Ring more than two days after the end of your period and will not allow you to pair the Ayola Ring and Ayola App.

The AYOLA System is composed of the Ayola Ring and the Ayola App. On the last day of your period (or within 24 hours after your period ends) you will pair your Ayola Ring with your Ayola App using Bluetooth™. Once the two are paired, you will insert the Ayola Ring into your vagina, and the Ayola System will begin to track your core body temperature. The AYOLA App will notify you when it has predicted your fertile window

Once you’ve already downloaded the Ayola App and set up an account:

• STEP 1: From the Home screen, tap “Period Started” on the day your period starts and use the selector to select the start date. Note: if you’re currently on your period, you will enter the historical day that your period began.
• STEP 2: Allow notifications when prompted – this is necessary for you to receive notification of your fertile window. If you accidentally disallow notifications, you may update your notification preferences in the phone app settings.
• STEP 3: When your period ends, tap “Period Ended” and use the selector to select the end date.

Note: If you need to adjust your period start or end dates, tap the corresponding date on the Calendar tab which reveals an edit button to modify the dates.

• STEP 4: On the day your period ends (or within 24 hours), pair your sensor as described in Section 5.3.

Note: Do not insert the Ayola Ring until after you have paired the Ayola Ring with the Ayola App and have seen a successful temperature reading in your app.”

The Ayola Ring continuously measures your core body temperature and sends your temperature information to the Ayola App. The Ayola App stores and analyzes your temperature measurements to detect your fertile window. The Ayola App will notify you when it has predicted your fertile window.

Click Sign In/Forgot Password/ Enter email/ Tap Email Me A Reset Code/once received Enter Password Reset Code/ New Ayola Password (see password requirements below)
Password Reset Requirements (after reset password code is requested and sent to their email)
Password reset code must match what was sent in the email
Password reset code becomes expired if the user leaves the page via the back button or app restart.
New password must be at least 6 characters in length
The email field must still match the email address where reset code was sent
Phone must still have internet access

To ensure an accurate fertile window prediction, the Ayola Ring should be inserted on the day your period ends (or within 24 hours after your period ends)(see Section 5.5 of the IFU). Do not pair your Ayola Ring until you are ready to insert it. The Ayola Ring should not be worn during your menstrual period.
The Ayola System is not effective if you start using the Ayola Ring more than two days after the end of your period and will not allow you to pair the Ayola Ring and Ayola App.”

Before you can use the Ayola Ring, you will have to set-up the Ayola App on your mobile phone.
To preserve battery life and to obtain the most accurate results, the Ayola Ring should be activated, paired and inserted within 24 hours after your menstrual period ends. The Ayola Ring will only work for 180 days after it is first activated, so the Sensor should not be activated until you are ready for insertion. The chart below details how to use the Sensor and the LED light modes associated with each action.
*see attachments for included chart*
Note: The Ayola App will not let you pair the device if your period end date was more than 2 days ago.
To pair your Ayola Ring with your Ayola App for the first time, follow the instructions below.
Wash hands with warm water and soap before handling the Ayola Ring.
Have the Ayola App opened on your mobile device
Have your pairing code ready (displayed on the Ayola Package)
Do not throw away the Ayola Package. You will need it to reference the pairing code and to store the Ayola Ring between cycles.
Tap ”Pair with Sensor” in the Ayola App. This will make the app scan for a sensor for 60 seconds.
TURN ON the Ayola Ring by squeezing the power button until the LED lights green.
The LED will be green and then turn blue to indicate it is attempting to pair.
Enter the Pairing Code in the app if prompted. You will have 30 seconds to enter the code before the Ayola Ring turns off.
Within a few seconds, the app will alert you that pairing was successful.
At this point, you may insert the Ayola Ring as described in How to insert Ayola Ring
Once these steps are complete, you may use your phone as usual. As long as the app is running in the background (do not force quit), the app will continue collecting temperatures and will notify you when you are entering your fertile window.
Troubleshooting Note: if at any time during your cycle you become concerned about whether or not the sensor and the app are still paired, you can remove the sensor and perform an instant data transfer as described in the Troubleshooting section.”

Sensor Failed to Pair – You will receive a pop-up alert if the sensor failed to pair. The pop-up alert will have instructions to re-attempt pairing your Ayola Ring.
App Failed to Find sensor – You will receive a pop-up alert if the app doesn’t discover the sensor during pairing. The pop-up alert will have instructions to re-attempt pairing your Ayola Sensor.
Too long since Bluetooth sync – You will receive a notification that it has been too long since the app synced with the Ayola Ring.
Temperature update without cloud sync – You will receive a notification that the Ayola App received temperature data that was not successfully saved to the cloud.”

Mobile device with a stable connection to the internet for downloading/installing software, registering the Ayola account, and uploading data to the secure cloud server is required. The Ayola Ring will store approximately 30 days of temperature data; a stable Bluetooth connection is required to transfer data from your Ayola Ring to the Ayola App.

You should use your Ayola Sensor from the last day of your current period to the first day of your next period, meaning you have to take out once you notice your menstruation. The AYOLA RING Sensor is not intended to be used for more than 29 consecutive days without removal and cleaning. You should not use the Ayola Ring during menstruation.

If you forget to re-insert your Ayola Ring after removing it temporarily, the accuracy of your fertile window predictions could be impaired. For the best results, keep your Ayola Ring in at all times during your active cycle (however, you must remove the Ayola Sesnor during menstruation). If you take the Ayola Ring out for any reason, it is best to clean and re-insert the Ayola Ring as soon as possible (within 1-2 hours).

A mobile device with a stable connection to the internet for downloading/installing software, registering the Ayola account, and uploading data to the secure cloud server is required. The Ayola Ring will store approximately 30 days of temperature data; a stable Bluetooth connection is required to transfer data from your Ayola Ring to the Ayola App.

After creating an account with the Ayola app and inserting the Ayola Sensor:

Your temperature data will be visible on the ‘“Home” screen once the Ayola App receives the first temperature reading.

The app will not display temperatures immediately. The sensor reads a temperature every 6 minutes and sends them over Bluetooth® in groups of 10 readings, thus temperatures sync with the app hourly.

The “sensor” tab displays the time of your next expected temperature sync.
Remember:

Once the Ayola Ring has paired with your mobile device, the Ayola App MUST be running in the foreground or background. If the app is completely closed, your data will not be transmitted, and you may miss your fertile window prediction.

Keep the Bluetooth on your mobile device on at all times – the Ayola App cannot receive temperature information if Bluetooth is turned off.

The Ayola App must have access to Wi-Fi or mobile data to upload your temperature and cycle information to the cloud.

To ensure the most accurate communication and data transfer from the Ayola Sensor, it is best to keep your mobile device in close proximity to your body during the expected sync times (e.g., in your front or back pocket or while you’re sleeping, on the nightstand next to your bed).

The Ayola App attempts to send temperature are saved to the cloud every time they are received from the Ayola App. Therefore if you uninstall and reinstall the Ayola App your data is still backed up on the cloud.

Yes, simply install the Ayola App on your new device and sign into your Ayola account with the email and password used while creating your Ayola account.

Device requirements:

A mobile device with a stable connection to the internet for downloading/installing software, registering the Ayola account, and uploading data to the secure cloud server is required. The Ayola Ring will store approximately 30 days of temperature data; a stable Bluetooth connection is required to transfer data from your Ayola Ring to the Ayola App.

Recommends a mobile device with the following specifications:

Operating System: iOS 11 or Android™ 8.0 or higher, preferably the most recent available version.

WiFi: Yes

Bluetooth: Yes, 4.2 Bluetooth

GPS: Yes

Battery Size: 2500mAh minimum

Number of Cells: 1

Note: An internet connection is used to register the device, and to download/upload data to the cloud system. The Ayola Ring will store your temperature data for approximately 30 days. Once the Ayola App receives temperature data, your mobile device will store all of your temperature information within the Ayola App.”

First, check to be sure the Ayola App is up to date with the latest version found on the Apple App store or the Google Play store. Check to be sure the WIFI and Bluetooth is on and the signal is strong. Then please contact customer service at www.ayolaring.com if the Ayola App crashes.

You must remove the Ayola Ring when your period starts, for periodic cleaning (at least every 29 days), and for sexual intercourse if desired. You do not need to turn off the Sensor when you remove it for periodic cleaning and intercourse.

NOTE: If the Ayola Ring has been out of your vagina for more than two hours during your cycle (when not on your menstrual period), it may affect the accuracy of your fertile window prediction. Therefore, except for when you remove the Ayola Ring during your menstrual period, you should re-insert the AyolaSensor as soon as possible after it has been removed.

The Ayola System is compatible with iOS and Android mobile devices that are Bluetooth 4.2 enabled and have one of the following Operating Systems: iOS 11 or Android™8.0 or higher.

The Ayola System is capable of displaying temperature in both Celsius and Fahrenheit. Temperature preferences can be set in the Ayola App when you set up your account.

It is recommended that the Ayola Ring be removed prior to passing through magnetic security checks to avoid detection and potential embarrassment. However, there is no safety risk associated with passing through a magnetic security check, should you face one unexpectedly.

You can start using your Ayola Sensor up to two days after the end of your period. The Ayola System is not effective if you start using the AyolaSensor more than two days after the end of your period and will not allow you to pair the Ayola Sensor and Ayola App. If it is more than two days after the end of your period, you will have to wait until the next month to start using the Ayola Sensor.

The Ayola Ring Sensor is not intended to be used while on your period and should be removed at the start of your period. The Sensor can be cleaned and stored in the Ayola Ring packaging until the end of your period.

The Ayola Ring Sensor does not need to be removed to have sexual intercourse. However, if there is any discomfort experienced by you or your partner, the ring may be removed for sexual intercourse. To enable the most accurate fertile window predictions, the sensor should be cleaned and re-inserted as soon as possible after having sexual intercourse.

If you forget to re-insert your Ayola Sensor after removing it temporarily, the accuracy of fertile window predictions could be impaired. For the best results, keep your Ayola Sensor in at all times during your active cycle. If you take the Ayola Sensor out for any reason, it is best to clean and re-insert the Ayola Sensor as soon as possible (within 1-2 hours).

If you are unable to remove your Ayola Sensor, don’t panic. Refer to the instructions for Sensor removal in the Instructions for Use. It may also be helpful to bear down (like when you are having a bowel movement) to assist with Sensor removal. If you are still unable to remove the Sensor, call your healthcare provider and schedule an appointment.
Note: it may help to use water-based lubrication gel on your finger to assist Sensor removal.

The Ayola Sensor is designed to be reused. If your Ayola Sensor falls out, you can clean and re-insert the Sensor.

If your sensor is off (not paired), simply download the app on the new mobile device and sign in. If your sensor is paired, then power off the sensor and begin the pairing process again on the new mobile device.

Yes. The Ayola Sensor has been validated for in-flight safety. Because the Sensor uses Bluetooth low energy, you are not required to turn it off during flight.

The Sensor takes temperatures every 6 minutes and transmits to the app hourly. Therefore, you may not see temperatures for the first hour, or until the succesful sync. Please see solutions above.

No. The Sensor can store up to 30 days of un-synced temperatures.

The graph in the “Home” screen displays your temperature values over time. The “Sensor” tab displays the last time temperatures were synced from the Sensor to the phone, and the last time the temperatures were synced to the cloud. Cloud syncs will be attempted every time temperatures are received from the Sensor.

It’s important to keep your mobile device as close to your body as possible during syncing, for about one minute or until a syncing occurs. Every woman’s body is different! You may find that having it in a back pocket works best. Depending on your anatomy, you may find placing your phone in front of you works well. Some women may find placing the mobile device in front of them works well, while others may need to place it closer to their side or back pocket. If syncing doesn’t work on the first try, don’t panic. Your temperature data is stored in the Sensor and will not be lost. Simply try a different position for your mobile device for the next scheduled sync, or take out the ring for the next sync and place near your phone. Sync once per day is sufficient for the prediction.

The Ayola Ring continuously measures your core body temperature and sends your temperature information to the Ayola App. The Ayola App stores and analyzes your temperature measurements to detect your fertile window. The Ayola App will notify you when it has predicted your fertile window.

The Ayola Ring is the same form factor as Estring. It has an outer diameter of 55 mm and an inner diameter of 37mm.

The Ayola Ring Sensor is designed to be one-size fits all.

It is not uncommon to experience mild discomfort during the first day of using the Ayola Sensor. If you feel discomfort, it is possible that the Ayola Ring may not be properly inserted. Use your finger to gently push the Ayola Ring further into your vagina to see if that helps. If the uncomfortable feeling does not resolve or if the level of discomfort is unacceptable, contact your healthcare provider for advice.

The exterior of the Ayola Ring is made of medical grade silicone.

If there is any discomfort experienced by you or your partner, the ring may be removed for sexual intercourse. To enable the most accurate fertile window predictions, the sensor should be cleaned and re-inserted as soon as possible after having sexual intercourse.

You must remove the Ayola Ring when your period starts, for periodic cleaning (at least every 29 days), and for sexual intercourse if desired. You do not need to turn off the Sensor when you remove it for periodic cleaning and intercourse.

NOTE: If the Ayola Ring has been out of your vagina for more than two hours during your cycle (when not on your menstrual period), it may affect the accuracy of your fertile window prediction. Therefore, except for when you remove the Ayola Ring during your menstrual period, you should re-insert the Ayola Ring as soon as possible after it has been removed.”

The Ayola Ring Sensor is not designed to have replaceable or rechargeable batteries. The Ayola Ring Sensor is designed to be used for up to 180 days.

The Ayola Ring Sensor has a temperature measurement accuracy of +/- 0.1°C. The Ayola Ring System predicts your day of ovulation with a standard deviation of 1.6 days and extrapolates your fertile window from that prediction. On average, Ayola predicts your fertile window 2.6 days prior to LH strips.

The Ayola Ring System is capable of displaying temperature in both Celsius and Fahrenheit. Temperature preferences can be set in the Ayola Ring App when you set up your account.

The Ayola Ring Sensor is not designed to have replaceable or rechargeable batteries. The Ayola Ring Sensor is designed to be used for up to 180 days. After 180 days of use, the battery life of the Ayola Ring Sensor will be depleted and the Sensor will need to be replaced.

We recommend that you clean and disinfect your Ayola Ring prior to insertion, and after each time it is removed.

Cleaning and disinfecting are not the same thing. Cleaning simply macroscopically visible contamination. Disinfecting kills germs and provides an extra level of safety. Some germs can live on surfaces for hours and even for days! You should follow the disinfection process provided as it has been shown to be effective in destroying dangerous bacteria and viruses.

The exterior of the Ayola Ring should only be cleaned and disinfected with a product such as DISPATCH Hospital Cleaner Disinfectant Towels™ or Oxivir Tb Wipes which™ have been tested and shown to be safe and effective. We recommend using DISPATCH towels (or another wipe that contains the active ingredient 0.65% of sodium hypochlorite) or Oxivir Tb Wipes (or another wipe that contains 0.5% accelerated hydrogen peroxide (AHP)). In the following procedure, the first disinfectant towel is used for cleaning and the second towel disinfects the Ayola Sensor.

Do not expose or submerge the sensor to or in boiling water. Exposing your sensor to boiling water will void the warranty.

Warnings for cleaning and disinfecting:

Do not use any glass or household cleaners on the device.

Do not put the device in the dishwasher or in the microwave.

DO NOT BOIL the device. (Exposing your sensor to boiling water will void the warranty)

Stop using the device and contact customer service immediately if you notice any of the following signs of deterioration:

The device does not turn on or off.

There is a change in color, or the device appears to be damaged.
Clean and disinfect the Ayola Ring with the disinfectant towels according to the following instructions.

Cleaning and disinfecting the Ayola System:

Wash your hands

Dispense the disinfectant towel from its package or container

Clean the entire surface of the Ayola Ring to remove any blood, dirt or vaginal discharge with one disinfectant towel.

Discard used towel according to the instructions provided with the disinfectant towel.

Dispense a second disinfectant towel from its package or container.

Disinfect the Ayola Ring with the second towel by wiping all outside surfaces thoroughly according to the instructions provided with the disinfectant towel.

Discard used towel according to the instructions provided with the disinfectant towel.

Wait at least one minute and make sure the Ayola Ring is completely air-dried before inserting the Ayola Sensor. Make sure that no bubbles from the cleaning and disinfecting agent remain.

If you’d like, you may rinse the Ayola Ring under cool running water to clear any residual disinfectant solution.

Note: You can find both types of cleaning wipes through online retailers such as Amazon.com”

Ayola Ring batteries are made from silver oxide (also called coin cell batteries) and have passed all applicable safety tests, in accordance with applicable standards and regulations.

The Ayola Ring is assembled at a certified manufacturing facility in Taiwan. The facility is certified to the highest standard of medical device quality manufacturing.

Yes! Ayola’s Bluetooth is safe because it uses very low power and is “on” less than 10 seconds per hour. Ayola’s Bluetooth uses 800 times less power than a mobile smartphone transmission, and follows Canadian regulations that sets limits for radio-frequency (RF) electromagnetic energy that are 50 times lower than scientific findings recommend. These regulations have been widely adopted by cell phone companies, Bluetooth accessory manufacturers, and Prima-Temp. “

The Ayola Ring has passed extensive testing to ensure its safety. Please read the full Instructions for Use before using the Ayola Ring and talk to your healthcare provider about any potential side effects you might experience with the Ayola Sensor. You should also report any adverse events to Customer Service.

Possible side effects may include:

Vaginal Irritation – The Ayola Ring is made of durable, medical-grade non-absorbent silicone. It should not irritate the inside of your vagina if cleaned and cared for properly. If at any time during your use of the Ayola Ring you experience any discomfort, discontinue use and contact your healthcare provider.

Vaginal Sensitization – One could have a sensitivity to any substance, but it is extremely rare to have a sensitivity to silicone. Studies indicate that silicone is biocompatible with the body. This is why silicone has been used in healthcare applications for over 50 years. If you do experience skin sensitivity, immediately discontinue use and contact your healthcare provider.

Vaginal Infection – Vaginal infections should be treated with appropriate antimicrobial therapy before using the Ayola System. If a vaginal infection develops during use of the Ayola System, then the Ayola Ring should be removed (see Section 5.9), and you should contact your healthcare provider.

Sensor Removal Difficulty – On rare occasions, the Ayola Ring may adhere to the vaginal wall, making the Ayola Ring removal difficult. Vaginal wall ulceration or erosion should be carefully evaluated. If an ulceration or erosion has occurred, consideration should be given to leaving the Ayola Ring out and not replacing it until healing is complete, in order to prevent the Ayola Ring from adhering to the healing tissue.

If you are unable to remove your Ayola Sensor, don’t panic. Refer to the instructions for sensor removal in this IFU (Section 5.9 “Removing and Turning Off the Sensor” and Section 11 “Frequently Asked Questions”). It may also be helpful to bear down (like when you are having a bowel movement) to assist with sensor removal. If you continue to have difficulty, call your healthcare provider and schedule an appointment.

Note: it may help to use water-based lubrication gel on your finger for sensor removal.

Toxic Shock Syndrome (TSS) –Toxic Shock Syndrome is a rare condition caused by the bacterium Staphylococcus aureus growing on blood or fluids in the vagina. For this reason, the Ayola Ring should not be worn during your menstrual period. Some of the symptoms are much the same as the flu, but they can become serious. STOP using the Ayola Ring immediately and call your healthcare provider right away if you have the following symptoms:

• sudden high fever (above 102℉ / 38.8 ℃)
• a sunburn-like rash
• diarrhea
• muscle aches
• dizziness
• vomiting
• fainting or feeling faint when standing up

Expulsion – the Ayola Ring can be accidentally expelled, for example during intercourse, or with straining during a bowel movement. If the Ayola Ring is accidentally expelled, wash your hands, and clean the Ayola Ring according to cleaning instructions (see Section 4) before you re-insert.

Partner Discomfort – if your partner experiences any discomfort from the Ayola Ring (i.e., penis discomfort or irritation), the Ayola Ring can be removed during intercourse. If the Ayola Ring was removed during intercourse, clean according to cleaning instructions (see Section 4) before you re-insert. To achieve the most accurate fertile window prediction, the sensor should be re-inserted as soon as possible (within 1-2 hours).

Tampon Use – you should not be wearing a Ayola Ring during your menstrual period, and therefore, you should not be using a tampon at the same time that you’re wearing the Ayola Sensor.

Other Possible Side Effects – this includes foreign body sensation, tissue irritation inside your vagina or cervix, vaginal discharge, and vaginal discomfort. Should you have any concerns about allergies, please consult your physician or dermatologist.”

Most women report that the Ayola Ring is comfortable and easy to use. The most common side effect is mild discomfort during the first day of using the Ayola Sensor. If you feel discomfort, it is possible that the Ayola Ring may not be properly inserted. Use your finger to gently push the Ayola Ring further into your vagina to see if that helps. If the uncomfortable feeling does not resolve or if the level of discomfort is unacceptable, contact your healthcare provider for advice.

The Ayola Ring does not need to be removed to have sexual intercourse. However, if there is any discomfort experienced by you or your partner, the sensor may be removed for sexual intercourse. To enable the most accurate fertile window predictions, the sensor should be cleaned and re-inserted as soon as possible after having sexual intercourse.

You must remove the ring to clean it after 29 days of continuous usage, however you might take it out when you would like to have intercourse or according to the IFU.

The Ayola RingSensor is intended to be cleaned using only the instructions in the Instructions for Use. The Ayola Ring Sensor should not be boiled, placed in the dishwasher or microwave, or cleaned with any agents or methods other than those listed in the IFU.

It is not uncommon to experience mild discomfort during the first day of using the Ayola Sensor. If you feel discomfort, it is possible that the Ayola Ring may not be properly inserted. Use your finger to gently push the Ayola Ring further into your vagina to see if that helps. If the uncomfortable feeling does not resolve or if the level of discomfort is unacceptable, contact your healthcare provider for advice.

The Ayola Ring Sensor is not intended to be used while on your period and should be removed at the start of your period. The Sensor can be cleaned and stored in the Ayola Ring packaging until the end of your period.

The Ayola Ring Sensor does not need to be removed to have sexual intercourse. However, if there is any discomfort experienced by you or your partner, the ring may be removed for sexual intercourse. To enable the most accurate fertile window predictions, the sensor should be cleaned and re-inserted as soon as possible after having sexual intercourse.

The Ayola Ring Sensor is intended to be cleaned using only the instructions in Section 4. The Ayola Ring Sensor should not be boiled, placed in the dishwasher or microwave, or cleaned with any agents or methods other than those listed in Section 4.

It is not uncommon to experience mild discomfort during the first day of using the Ayola Ring Sensor. If you feel discomfort, it is possible that the Ayola Ring Sensor may not be properly inserted. Use your finger to gently push the Ayola Ring Sensor further into your vagina to see if that helps. If the uncomfortable feeling does not resolve or if the level of discomfort is unacceptable, contact your healthcare provider for advice.

The Ayola Ring Sensor should not be used if you currently have any vaginal infections. Any infections should be treated and cleared up before using the Ayola Ring Sensor. If you develop any infections while using the Ayola Ring Sensor, the Sensor should be removed, cleaned, and stored until the infection has cleared up.

The Ayola Ring Sensor is yours and is intended to be used by only you. Sharing the Ayola Ring Sensor with others presents a hygienic risk and will invalidate your personal results.

Each Ayola Ring Sensor is supplied with a Bluetooth Pairing Code. The Ayola Ring Sensor will only communicate with the Ayola Ring App if the Bluetooth Pairing Code has been entered. Being around another active Ayola Ring Sensor will not affect your results.

It is recommended that the Ayola Ring Sensor be removed prior to passing through magnetic security checks to avoid detection and potential embarrassment. However, there is no safety risk associated with passing through a magnetic security check, should you face one unexpectedly.

Yes. The Ayola Ring Sensor has been validated for in-flight safety. Because the Sensor uses Bluetooth low energy, you are not required to turn it off during flight.